Obesity is one of the largest problems of public health. Despite the taken measures in the treatment of obesity, the disease continues to spread. Overweight is not only an aesthetic problem, but risk factor for the development of various diseases. Obese patients are most frequently exposed to the risk of different cardiovascular diseases, including: hypertension, ischemic heart disease, stroke and peripheral occlusive arterial disease.
Weight loss helps to prevent or to control the influence of obesity on the associated diseases. Obese patients are rarely able to reduce the weight on their own. They cannot control eating behavior, so non-pharmacological therapy is ineffective in most cases. In the case when the change of lifestyle does not allow reducing body weight, the medication called Duromine is included in the non-drug therapy for obesity treatment.
Lifestyle modification includes the improvement of daily diet and increase in physical activity. Change in eating behavior and active lifestyle should be started: before pharmacotherapy of weight correction, during the pharmacotherapy and after the discontinuation of Duromine drug. Medical treatment of obesity by means of Duromine pills is just a part of general therapy of overweight management.
Duromine drug for obesity treatment is usually prescribed to patients with excess body weight having concomitant diseases, as well as to patients without concomitant diseases whose BMI above 30. The use of Duromine pills together with hypocaloric diet and exercise leads to weight loss about 3-5 kgs a month. Regular use of Duromine within 24 weeks allows achieving the optimal body weight.
The use of Duromine drug less than 24 weeks (a course of obesity therapy) will not provide a therapeutic effect. Because, pharmacological action of Duromine is increasing progressively. Weight continues to decrease even after the discontinuation of Duromine tablets only in the case if the patient adheres to dietary restrictions and does exercise. Due to the fact that Duromine drug provides the anorexigenic effect, the obese patients easier to give up fatty and high -calorie food.
Modification of eating behavior allows patients taking Duromine tablets to refuse from extra snacks and herewith to feel saturation from the use of small amount of food. Duromine not only reduces appetite but also normalizes digestive and metabolic processes. When using Duromine, the accelerated metabolism makes the body to spend more energy even in minimum physical activity that contributes to the burning of subcutaneous fat.
Given that obesity violates lipid metabolism, Duromine use provides not only weight loss but also normalizes lipid metabolism. Thus, low-density lipoprotein cholesterol and triglyceride level decrease, as well as high-density lipoprotein cholesterol level increases in patients taking Duromine pills. It is possible that to normalize lipid metabolism, it is necessary to include lipid-lowering drug, such as Simvastatin or Atorvastatin in the drug therapy with Duromine.
Given that Duromine use not only decreases body weight but also accelerates the metabolic process and improves lipid profile, dosage reduction of lipid-lowering drugs or their complete cancellation may be required. Thus, regular use of Duromine provides weight loss and normalizes lipid metabolism, as well as reduces the risk of cardiovascular diseases.
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